Irritable bowel syndrome презентация

Слайд 1JSC “Medical University Astana”
Department of Internal Diseases №1
Done by: Suleymanov M.
463

GM
Checked by: Dr. scient. med.,professor
Baidurin S.A.

Astana 2018

IRRITABLE BOWEL SYNDROME


Слайд 2Introduction






First described in 1771.
50% of patients present

sufferers are symptom free after 5 years. GPs will diagnose one new case per week.
GPs will see 4-5 patients a week with IBS.
Point prevalence of 40-50 patients per 2000 patients.

4



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World Prevalence of IBS

Adapted from Camilleri M, et al. Aliment Pharmacol

Ther. 1997;11:3.

Muller-Lisners et al. Digestion. 2001;64:200.

Canada

13.5%

US 10-20%

Peru

18%

Nigeria 30%

France 9.4%

UK 22%

Australia

12%

New Zealand

17%

China 23%

Japan 25%

Germany

12%


Слайд 4

Prevalence of IBS


Слайд 5




Types of IBS
:IBS can be subdivided into
Constipation-predominant :the person tends to

alternate constipation with normal stools. Symptoms of abdominal cramping or aching are
.commonly triggered by eating
Diarrhea-predominant : the person tends to experience diarrhea first thing in the morning or after eating. The need to go to the toilet is typically
.urgent and cannot be delayed
(Alternating constipation and diarrhea(IBS-A -3

-1

-2

or (IBS-M) mixed IBS

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The Positive Diagnosis of IBS:
A Symptom-Based Approach
Adapted from Paterson et al.

Can Med Assoc J. 1999;161:154.

American Gastroenterological Association. Gastroenterology. 1997;112:2120.

























































































































































































































































































































































































































































































































































Identify Current Primary Symptoms
Abdominal pain / discomfort
Bloating
Constipation/Diarrhea

Look for ‘Red Flags’ Based on:
History
Physical exam
Laboratory tests

Perform Selected Physical and Diagnostic Tests to Rule Out Organic Disease


Make a Positive Diagnosis




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Identify Red Flags
νHistory
ν Unintentional weight loss
ν Onset in older patient (>50

years)

ν Family history of cancer or IBD

νInitial labs

↓ HGB
↑ WBC
↑ ESR
Abnormal chemistry
↑ TSH

νPhysical

ν Abnormal exams

ν Rectal bleeding / obstruction

ν Positive flexible sigmoidoscopy

or colonoscopy (>50 years)

Adapted from a technical review. Gastroenterology. 1997;112:2120.

Paterson et al. Can Med Assoc J. 1999;161:154.

Camilleri et al. Aliment Pharmacol Ther. 1997;11:3.

Red Flags



Слайд 8The balance of IBS diagnosis


Слайд 9Association of bowel symptoms with stool consistency

Tillisch et al Am J

Gastroenterol. 2005; 100:896-904






Слайд 10
Defining Stool Consistency
Bristol Stool Form Scale


















Hard
Normal
Loose



Слайд 11Changes to IBS classification Rome III Summary
No change to basic criteria
Length

of time needed to define chronicity reduced to 6 months
Threshold ≥3 days / month introduced for frequency of pain / discomfort
Subtyping simplified (stool consistency)
Stability of subtypes and link to other features like visceral sensitivity and response to treatment remain to be determined

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Manning
Kruis
Rome
Rome I
Rome II
Rome III
1978
1984
1989 1990
1999
2006



















IBS diagnostic criteria
Rome IV
2016
INTERNAL USE ONLY. DO NOT

COPY. DO NOT DISTRIBUTE EXTERNALLY.

Слайд 13


oidoscopy- 1
the lower part of the colon
(sigmoid)
with
ted
tube
(sigmoidoscope
18

Additional tests

:-Flexible sigm
This test examines
).

a flexible, ligh

Слайд 14


2- Computerized tomography (CT) scan :-
CT scans produce
cross-sectional
X-ray
images
of

internal
organs
19





Слайд 15
3- Colonoscopy :-
In some cases, your doctor may perform this
diagnostic test,

in which a small, flexible tube is


used

to

examine

the

entire

length

of

the

colon.

20



Слайд 16
4- Lactose intolerance tests :-
Lactase is an enzyme you need to

digest the sugar

-

.
If

found in dairy products
you don't produce this enzyme, you may have

-

problems including abdominal pain,
diarrhea

gas and

.

,To find out if this is the cause of your
your doctor may order a breath test
or ask you to exclude milk
and milk products from your
.diet for several weeks

symptoms-

21




Слайд 18TREATMENT
PATIENT EDUCATION
DIETARY INTERVENTION
PHARMACOTHERAPY
PSYCHOTHERAPY/COGNITIVE AND BAHAVIOR THERAPY
HYPNOTHERAPY


Слайд 19


















































































Drug Treatment of IBS
Abdominal pain/discomfort
Antispasmodics
Antidepressants
— TCAs/SSRIs
Bloating and distention
Antiflatulents
Antispasmodics
Dietary modification
Constipation
Fiber
Laxatives
PEG solutions
Diarrhea
Opioids
—Loperamide
Cholestyramine

Abdominal
pain/
discomfort
Bloating/
distention
Altered bowel
function
None

of these medications effectively treat the multiple symptoms of IBS;

they may exacerbate individual symptoms (eg, fiber and bloating,

antispasmodic, constipation).


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