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Nucleic acids презентация
Содержание
- 1. Nucleic acids
- 2. Frederick Griffith British physician, pathologist, bacteriologist Known for discovery of pneumococcal transformation
- 3. Griffith’s experiment
- 4. Oswald Avery Canadian-born American physician and medical and medical researcher.
- 5. dСMP
- 6. The principal bases in DNA PURINES PYRIMIDINES
- 11. The greatest discovery!
- 12. Form of DNA А-form
- 13. Histones H2A, H2B, H3 и H4 –
- 17. A simple interphase organization From Prof. de Jong lecture, 2006
- 18. Interphase loop model H4 Acetylated euchromatin DNA
- 19. Trihybrid 1: CC x
- 20. FISH: Human chromosomes
- 21. Расположение 23 хромосом человека в прометафазе фибробластов
Frederick Griffith
British physician, pathologist, bacteriologist Known for discovery of pneumococcal transformation
Слайд 2Frederick Griffith
British physician, pathologist, bacteriologist
Known for discovery of pneumococcal transformation
Слайд 4Oswald Avery
Canadian-born American physician
and medical and medical researcher.
The major part
of his career was spent
at the Rockefeller University
Hospital in New York City
Слайд 13Histones
H2A, H2B, H3 и H4 – similar between distant species:
-
Н3 of calf differs from Н3 sea-urchin only in one amino acid and from green peas Н3 in tree amino acids
Н1 – more variable
- birds posses Н5 histone in erythrocytes instead H1
Н1 – more variable
- birds posses Н5 histone in erythrocytes instead H1
Слайд 18Interphase loop model
H4 Acetylated euchromatin
DNA methylated heterochromatin
From Prof. de Jong lecture,
2006
Слайд 19
Trihybrid 1: CC x (FF x RR)
A. fistulosum - Biotin, CY3
A. roylei - FITC
A. cepa - block DNA,
DAPI
A. roylei - FITC
A. cepa - block DNA,
DAPI
Mitosis: metaphase
Khrustaleva & Kik (1998) Theor Appl Genet 96: 8-14
