Anaerobic Gram-Positive Spore-Forming Bacilli презентация

Содержание

See Lecture Handouts

Слайд 2


Слайд 3See Lecture Handouts


Слайд 5Spores
Clostridium form endospores under adverse environmental conditions
Spores are a survival mechanism
Spores

are characterized on the basis of position, size and shape
Most Clostridium spp., including C. perfringens and C. botulinum, have ovoid subterminal (OST) spores
C. tetani have round terminal (RT) spores


Слайд 6Clostridium Associated Human Disease


Слайд 7Clostridium perfringens


Слайд 9Summary of C. perfringens Infections


Слайд 10Micro & Macroscopic C. perfringens


Слайд 11Summary of C. perfringens Infections (cont.)


Слайд 12Clostridial Cellulitis


Слайд 13C. perfringens Virulence Factors


Слайд 14Exotoxins Associated with C. perfringens Types A-E
Major


Слайд 15C. perfringens Nagler Reaction
NOTE: Lecithinase (α-toxin; phospholipase) hydrolyzes phospholipids in egg-yolk

agar around streak on right. Antibody against α-toxin inhibits activity around left streak.

Слайд 16Clostridium tetani


Слайд 18Summary of C. tetani Infections


Слайд 19Summary of Clostridium tetani Infections (cont.)


Слайд 20Clostridium tetani Gram Stain
NOTE: Round terminal spores give cells a “drumstick”

or “tennis racket” appearance.

Слайд 21Clinical Forms of Tetanus


Слайд 22Opisthotonos in Tetanus Patient


Слайд 23Risus Sardonicus in Tetanus Patient


Слайд 24Mechanism of Action of Tetanus Toxin


Слайд 25Clostridium botulinum


Слайд 26Summary of C. botulinum Infections


Слайд 27Summary of C. botulinum Infections (cont.)


Слайд 29Mechanism of Action of Botulinum Toxin


Слайд 30Rates of Isolation of C. botulinum and Botulinum Toxin


Слайд 31Clostridium dificile


Слайд 32Summary of C. dificile Infections


Слайд 33Summary of C. dificile Infections (cont.)


Слайд 34Antibiotic-Associated Colitis
Plaque


Слайд 35Antibiotic-Associated Colitis


Слайд 36C. dificile Virulence Factors


Слайд 37Other Clostridium


Слайд 38Virulence Factors Associated with Other Clostridium


Слайд 40REVIEW
Clostridium


Слайд 42See Lecture Handouts
REVIEW


Слайд 43Spores
Clostridium form endospores under adverse environmental conditions
Spores are a survival mechanism
Spores

are characterized on the basis of position, size and shape
Most Clostridium spp., including C. perfringens and C. botulinum, have ovoid subterminal (OST) spores
C. tetani have round terminal (RT) spores

REVIEW


Слайд 44Review of Clostridium perfringens
REVIEW


Слайд 46Micro & Macroscopic C. perfringens
REVIEW


Слайд 47C. perfringens Virulence Factors
REVIEW


Слайд 48Exotoxins Associated with C. perfringens Types A-E
Major
REVIEW


Слайд 49C. perfringens Nagler Reaction
NOTE: Lecithinase (α-toxin; phospholipase) hydrolyzes phospholipids in egg-yolk

agar around streak on right. Antibody against α-toxin inhibits activity around left streak.

REVIEW


Слайд 50Review of Clostridium tetani


Слайд 52Clostridium tetani Gram Stain
NOTE: Round terminal spores give cells a “drumstick”

or “tennis racket” appearance.

REVIEW


Слайд 53Clinical Forms of Tetanus
REVIEW


Слайд 54Mechanism of Action of Tetanus Toxin
REVIEW


Слайд 55Review of Clostridium botulinum


Слайд 57Mechanism of Action of Botulinum Toxin
REVIEW


Слайд 58Review of Clostridium dificile


Слайд 59Summary of C. dificile Infections
REVIEW


Слайд 60Summary of C. dificile Infections (cont.)
REVIEW


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