Презентация на тему Serious Games for Bioinformatics Education

Презентация на тему Презентация на тему Serious Games for Bioinformatics Education, предмет презентации: Образование. Этот материал содержит 45 слайдов. Красочные слайды и илюстрации помогут Вам заинтересовать свою аудиторию. Для просмотра воспользуйтесь проигрывателем, если материал оказался полезным для Вас - поделитесь им с друзьями с помощью социальных кнопок и добавьте наш сайт презентаций ThePresentation.ru в закладки!

Слайды и текст этой презентации

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Serious Games for Bioinformatics Education

Benjamin Good
The Scripps Research Institute

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Why games?


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is useful for:
getting their attention
holding their attention


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Recruiting bioinformaticians

“We're hopefully going to change the way science is done,
and who it's done by”

Zoran Popović
University of Washington
Foldit, a game for protein folding

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Foldit players come from many backgrounds

Top 50 players
largest group..

Majority have no training in biochemistry

Cooper, Seth, et al. "Predicting protein structures with a multiplayer online game." Nature 466.7307 (2010): 756-760.

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Teaching with games

“The use of educational games within learning environments raises motivation, increases interest in the subject matter, intensifies information retention, encourages collaboration, and improves problem-solving skills.”

Schneider, Maria Victoria, and Rafael C. Jimenez. "Teaching the fundamentals of biological data integration using classroom games." PLoS computational biology 8.12 (2012)

Quoting: Michael D, Chen S (2006) Serious games: games that educate, train and inform. Boston: Thomson Course Technology.”

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Games can be used to teach

Stegman, Melanie. "Immune Attack players perform better on a test of cellular immunology and self confidence than their classmates who play a control video game." Faraday Discuss 169 (2014): 1-20.

Immune Attack

High school students
First person shooter game
Significantly improves understanding of concepts in immunology

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Finding educational bioinformatics games…

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Educational games

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TBG – select a protein

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TBG: fly around to hit the next amino acid on your list

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4bases (Rostlab, masters thesis)

Click the next base in time as the sequence scrolls by.

Introduces concept of DNA sequencing

Click next base

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Goal: introduce the concepts and purposes of DNA sequence comparisons (BLAST) and distributed computing to high school students
First person game set in 3-d world beset by an influenza pandemic.

Perry, Daniel, et al. "Human centered game design for bioinformatics and cyberinfrastructure learning." Proceedings of the Conference on Extreme Science and Engineering Discovery Environment: Gateway to Discovery. ACM, 2013.

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MAX5 starting screen 1

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MAX5 starting screen 2

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MAX5 “blasting” to detect what a sample is infected with

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MAX5 BLAST analysis

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MAX5 alignment viewer

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MAX5 sample hunting

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MAX5 parallel computing

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MAX5, TBG, 4Bases,…

Useful introductions.
Useful for recruiting.

Very high-level – shallow learning.

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Bioinformatics education games

All examples of gamifying tasks in bioinformatics.
None built for the purpose of education!

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Genes in Space

Fly a spaceship
(oh by the way you are helping cancer research)
300,000 downloads 3 months..
Cancer UK project.

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The Cure game

Alternate turns picking a gene from a “board” of 25

Your hand

Opponents hand

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Classroom uses

The Cure story (Antoine Taly) http://tinyurl.com/talycure
Goal: understand the concept of Biomarkers
Watch short video
Play The Cure game (involves picking genes useful for predicting breast cancer survival)
Create custom predictive decision tree
Write essay about what you did

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World of Warcraft
Super Mario Brothers
The Game of Life

Angry Birds
The Sims

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Game: defining traits

A goal
Feedback system
Voluntary participation

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Running – no

Answering questions about programming – no

Programming – no

A goal
Feedback system
Voluntary participation

Nike+ Fuelband – yes

Stackoverflow – yes

TopCoder.com – yes

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Google: “the application of typical elements of game playing to other areas of activity…”

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Gamified education.

Sort of games…

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Students form teams
In each of a series of “innings”:
They are presented with (or find themselves) lists of proteins
They look up articles about them and try to create GO annotations.
The team gets points for complete, correct annotations
At the end of the inning they can “challenge” the annotations of other teams and steal their points. (Like Scrabble!!)

Jim Hu, Texas A&M (TAMU) http://gonuts.tamu.edu/wiki/index.php/Cacao_rules

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CACAO participation

Since 2010,
1000+ students
15 universities
2,800+ new, acceptable annotations
No empirical evidence that gamification helps, but anecdotally everyone likes it..

Example teams from 2013

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Rosalind is a platform for learning bioinformatics and programming through problem solving.

Python Village
(learn programming)

Bioinformatics Stronghold
(learn algorithms)

Bioinformatics Armory
(learn tools)

Textbook exercises

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“Storm the bioinformatics stronghold now!”

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Problems: 228 (total), users: 18194, attempts: 296869, correct: 172873

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Rosalind user profile

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Rosalind leaderboard

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Use of games/gamification in bioinformatics education

Expressivity: Number and depth of learnable concepts


Benefits: recruiting, engagement

Holy Grail

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Future Directions

Slowly pushing towards the holy grail(s)
Example: ‘Cyclo6’ will attempt to teach advanced organic chemistry – to be released on the app store this fall.
Removing boundaries that divide scientific games from each other and from other games
Genes in Space team – integration directly inside the context of “The Impossible Line” by Chilingo

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System for teachers to create lessons that move students through specified levels of multiple games.

Jerome Waldispuhl,
McGill University, Phylo

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Jerome Waldispuhl (Phylo)
Daniel Perry (MAX5)
Antoine Taly (pioneering the use of games (Foldit, Phylo, The Cure) in his courses)
Julia Winter (Cyclo6)
Jim Hu (CACAO)
Melanie Stegman


Andrew Su

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Heroic Purpose

Biology and medicine provide a heroic purpose – not unlike the more standard purpose of saving the world from aliens.
There are great games to be made and great bioinformaticians to be discovered!


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Finding educational bioinformatics games

Lists about 95 games related to science
57 are tagged with “biology”
2 with “computer science”
None focus on bioinformatics learning objectives.

Melanie Stegman
Federation of American Scientists

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Google define:fun “enjoyment, amusement, or lighthearted pleasure”
“Fun” from game design guru Raph Koster
“the act of mastering a problem mentally”
“the feedback the brain gives us when we are absorbing patterns for learning purposes”
“fun is about learning in a context where there is no pressure, and that is why games matter”

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