Serious Games for Bioinformatics Education презентация

Содержание

Why games? Attention!!!

Слайд 1Serious Games for Bioinformatics Education
Benjamin Good
The Scripps Research Institute
@bgood


Слайд 2Why games?
Attention!!!


Слайд 3is useful for:
Recruiting
getting their attention
Engaging
holding their attention
Attention


Слайд 4Recruiting bioinformaticians
“We're hopefully going to change the way science is done,


and who it's done by”

Zoran Popović
University of Washington
Foldit, a game for protein folding


Слайд 5Foldit players come from many backgrounds
Top 50 players
Busn/finance/legal
largest group..
Majority

have no training in biochemistry

Cooper, Seth, et al. "Predicting protein structures with a multiplayer online game." Nature 466.7307 (2010): 756-760.


Слайд 6Teaching with games
“The use of educational games within learning environments raises

motivation, increases interest in the subject matter, intensifies information retention, encourages collaboration, and improves problem-solving skills.”

Schneider, Maria Victoria, and Rafael C. Jimenez. "Teaching the fundamentals of biological data integration using classroom games." PLoS computational biology 8.12 (2012)

Quoting: Michael D, Chen S (2006) Serious games: games that educate, train and inform. Boston: Thomson Course Technology.”


Слайд 7Games can be used to teach
Stegman, Melanie. "Immune Attack players perform

better on a test of cellular immunology and self confidence than their classmates who play a control video game." Faraday Discuss 169 (2014): 1-20.

Immune Attack
http://ImmuneDefenseGame.com

High school students
First person shooter game
Significantly improves understanding of concepts in immunology


Слайд 8Finding educational bioinformatics games…


Слайд 9Educational games


Слайд 10TBG – select a protein


Слайд 11TBG: fly around to hit the next amino acid on your

list



Слайд 124bases (Rostlab, masters thesis)
Click the next base in time as the

sequence scrolls by.

Introduces concept of DNA sequencing

Click next base


Слайд 13MAX5
Goal: introduce the concepts and purposes of DNA sequence comparisons (BLAST)

and distributed computing to high school students
First person game set in 3-d world beset by an influenza pandemic.
http://gamestem.com/portfolio/max5-storyline-1/

Perry, Daniel, et al. "Human centered game design for bioinformatics and cyberinfrastructure learning." Proceedings of the Conference on Extreme Science and Engineering Discovery Environment: Gateway to Discovery. ACM, 2013.


Слайд 14MAX5 starting screen 1


Слайд 15MAX5 starting screen 2


Слайд 16MAX5 “blasting” to detect what a sample is infected with


Слайд 17MAX5 BLAST analysis


Слайд 18MAX5 alignment viewer


Слайд 19MAX5 sample hunting


Слайд 20MAX5 parallel computing


Слайд 21MAX5, TBG, 4Bases,…
Plusses
Useful introductions.
Useful for recruiting.
Minuses
Very high-level – shallow learning.


Слайд 22Bioinformatics education games
All examples of gamifying tasks in bioinformatics.
None built for

the purpose of education!

Слайд 23Genes in Space
Fly a spaceship
(oh by the way you are helping

cancer research)
300,000 downloads 3 months..
Cancer UK project.

Слайд 24The Cure game
Alternate turns picking a gene from a “board” of

25

Your hand

Opponents hand


Слайд 25Classroom uses
The Cure story (Antoine Taly) http://tinyurl.com/talycure
Goal: understand the concept of

Biomarkers
Watch short video
Play The Cure game (involves picking genes useful for predicting breast cancer survival)
Create custom predictive decision tree
Write essay about what you did

Слайд 26“Game”
Soccer
Chess
World of Warcraft
Halo
Super Mario Brothers
The Game of Life
Monopoly
Angry Birds
Poker
Doom
Pacman
The Sims
Spore
Civilization


Слайд 27Game: defining traits
A goal
Rules
Feedback system
Voluntary participation


Слайд 28Games…?
Running – no

Answering questions about programming – no

Programming – no


A goal
Rules
Feedback

system
Voluntary participation


Nike+ Fuelband – yes



Stackoverflow – yes


TopCoder.com – yes


Слайд 29Gamification
Google: “the application of typical elements of game playing to other

areas of activity…”

Слайд 30Gamified education.
Sort of games…


Слайд 31CACAO Rules
Students form teams
In each of a series of “innings”:
They are

presented with (or find themselves) lists of proteins
They look up articles about them and try to create GO annotations.
The team gets points for complete, correct annotations
At the end of the inning they can “challenge” the annotations of other teams and steal their points. (Like Scrabble!!)

Jim Hu, Texas A&M (TAMU) http://gonuts.tamu.edu/wiki/index.php/Cacao_rules


Слайд 32CACAO participation
Since 2010,
1000+ students
15 universities
2,800+ new, acceptable annotations
No empirical

evidence that gamification helps, but anecdotally everyone likes it..

Example teams from 2013



Слайд 33Rosalind.info
Rosalind is a platform for learning bioinformatics and programming through problem

solving.

Python Village
(learn programming)

Bioinformatics Stronghold
(learn algorithms)

Bioinformatics Armory
(learn tools)

Textbook exercises


Слайд 34“Storm the bioinformatics stronghold now!”


Слайд 35Problems: 228 (total), users: 18194, attempts: 296869, correct: 172873


Слайд 36Rosalind user profile


Слайд 37Rosalind leaderboard


Слайд 38Use of games/gamification in bioinformatics education
Expressivity: Number and depth of learnable

concepts


Fun

Benefits: recruiting, engagement

Holy Grail


Слайд 39Future Directions
Slowly pushing towards the holy grail(s)
Example: ‘Cyclo6’ will attempt

to teach advanced organic chemistry – to be released on the app store this fall.
Removing boundaries that divide scientific games from each other and from other games
Genes in Space team – integration directly inside the context of “The Impossible Line” by Chilingo
Yako.io

Слайд 40http://yako.io
System for teachers to create lessons that move students through specified

levels of multiple games.

Jerome Waldispuhl,
McGill University, Phylo

Слайд 41Acknowledgements
Jerome Waldispuhl (Phylo)
Daniel Perry (MAX5)
Antoine Taly (pioneering the use of games

(Foldit, Phylo, The Cure) in his courses)
Julia Winter (Cyclo6)
Jim Hu (CACAO)
Melanie Stegman
http://www.sciencegamecenter.org
http://ImmuneDefenseGame.com

Funding

Andrew Su


Слайд 43Heroic Purpose
Biology and medicine provide a heroic purpose – not unlike

the more standard purpose of saving the world from aliens.
There are great games to be made and great bioinformaticians to be discovered!

BIOINFORMATICIAN


Слайд 44Finding educational bioinformatics games
http://www.sciencegamecenter.org/
Lists about 95 games related to science
57 are

tagged with “biology”
2 with “computer science”
None focus on bioinformatics learning objectives.

Melanie Stegman
Federation of American Scientists


Слайд 45Fun
Google define:fun “enjoyment, amusement, or lighthearted pleasure”
“Fun” from game design guru

Raph Koster
“the act of mastering a problem mentally”
“the feedback the brain gives us when we are absorbing patterns for learning purposes”
“fun is about learning in a context where there is no pressure, and that is why games matter”

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