Sexually transmitted bacterial diseases презентация

Содержание

PLAN Morphology Culture Antigenic structure Virulence factors Pathogenesis Immunity Clinical syndromes Epidemiology Laboratory diagnosis Treatment Prevention

Слайд 1SEXUALLY TRANSMITTED BACTERIAL DISEASES


Слайд 2PLAN
Morphology
Culture
Antigenic structure
Virulence factors
Pathogenesis
Immunity
Clinical syndromes
Epidemiology




Laboratory diagnosis
Treatment
Prevention


Слайд 3
A 28-year-old hair dresser complained of a painless small ulcer on

the penis during the last 2 weeks. When asked, he said he had repeated sexual relation with a female sexual worker approximately many months back. On examination, the pus exudate from the smear did not reveal any Treponema. Serum sample was found to be positive for syphilis by the VDRL test. ELISA for HIV was negative




Слайд 4TREPONEMA PALLIDUM: MORPHOLOGY


Слайд 5TREPONEMA PALLIDUM : ANTIGENIC STRUCTURE
Cardiolipin antigen

T. pallidum group-specific antigen

T.

pallidum species-specific antigen

Слайд 6TREPONEMA PALLIDUM : VIRULENCE FACTORS


Слайд 7TREPONEMA PALLIDUM : PATHOGENESIS


Слайд 8TREPONEMA PALLIDUM : CLINICAL SYNDROMES
Venereal syphilis (transmitted by sexual contact)
Nonvenereal syphilis

(congenital syphilis and occupational syphilis)

Слайд 9TREPONEMA PALLIDUM : EPIDEMIOLOGY


Слайд 10TREPONEMA PALLIDUM : LABORATORY DIAGNOSIS
Microscopy
Direct antigen detection
Serodiagnosis:
Nontreponemal tests (standard tests of

syphilis: STS):
Wasserman complement fixation test
Kahn’s tube flocculation test
VDRL test
Rapid plasma reagin (RPR) test
Treponema-specific tests:
T. pallidum immobilization test
T. pallidum agglutination test
T. pallidum immune adherence test
Fluorescent treponemal antibody test
TPHA test
Enzyme immunoassay

Слайд 11TREPONEMA PALLIDUM : LABORATORY DIAGNOSIS


Слайд 12
A 6-year-old boy attended the Ophthalmology OPD with symptoms of conjunctivitis

of the right eye. Examination showed follicular hypertrophy with diffuse inflammation that had affected the entire conjunctiva along with pannus formation. Iodine staining of conjunctival scrapings demonstrated inclusion bodies of Chlamydia trachomatis. The condition was diagnosed as trachoma.

Слайд 13CHLAMYDIA TRACHOMATIS: MORPHOLOGY


Слайд 14CHLAMYDIA TRACHOMATIS: CULTURE


Слайд 15CHLAMYDIA TRACHOMATIS: ANTIGENIC STRUCTURE
Genus-specific antigen
Species-specific antigen
Serotype-specific antigen

Typing of species
trachoma biovar causing

trachoma and inclusion conjunctivitis (TRIC) – 13 serotypes,
lymphogranuloma venereum (LGV) biovar causing LGV – 5 serotypes, and
serovars causing mouse pneumonitis

Слайд 16CHLAMYDIA TRACHOMATIS: VIRULENCE FACTORS
The ability to multiply intracellularly in the infected

cell is the key mechanism of virulence of C. trachomatis.
The bacteria prevent fusion of phagolysosome with cellular liposomes, thereby preventing intracellular killing of the bacteria by the host cell.
Repeated infections caused by C. trachomatis contribute to pathology seen in the infected eye in trachoma.

Слайд 17CHLAMYDIA TRACHOMATIS: PATHOGENESIS


Слайд 18CHLAMYDIA TRACHOMATIS: CLINICAL SYNDROMES
Lymphogranuloma venereum
Ocular LGV
Trachoma
Adult inclusion conjunctivitis
Neonatal conjunctivitis
Infant pneumonia
Urogenital infections


Слайд 19CHLAMYDIA TRACHOMATIS: CLINICAL SYNDROMES


Слайд 20CHLAMYDIA TRACHOMATIS: LABORATORY DIAGNOSIS
Microscopy
Culture
Antigen detection
Serodiagnosis
Frei’s skin test


Слайд 21
A 22-year-old female complained of lower abdominal pain on and off

for the last 3 months. She complained of a feeling of heaviness in the pelvis and pain during sexual intercourse. On examination, a tender mass was found to the right side during examination. Gram staining of cervical swab showed plenty of pus cells and a few Gram-negative cocci. She gave a history of allergy to penicillins.

Слайд 22NEISSERIA GONORRHOEAE: MORPHOLOGY


Слайд 23NEISSERIA GONORRHOEAE: CULTURE


Слайд 24NEISSERIA GONORRHOEAE: VIRULENCE FACTORS


Слайд 25NEISSERIA GONORRHOEAE: PATHOGENESIS


Слайд 26NEISSERIA GONORRHOEAE: CLINICAL SYNDROMES
gonorrhea,
disseminated gonococcal infections (DGI),
ophthalmia neonatorum, and


other gonococcal diseases

Слайд 27NEISSERIA GONORRHOEAE: LABORATORY DIAGNOSIS
Microscopy
Culture
Antigen detection
SerodiagnosiS


Слайд 28NEISSERIA GONORRHOEAE: CLINICAL SYNDROMES
gonorrhea,
disseminated gonococcal infections (DGI),
ophthalmia neonatorum, and


other gonococcal diseases

Слайд 29NEISSERIA GONORRHOEAE: LABORATORY DIAGNOSIS
Microscopy
Culture
Antigen detection
SerodiagnosiS


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