Skoltech Institute Selection Event, Moscow, 2016
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Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice презентация
Содержание
- 1. Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice
- 2. From R&D Systems website - www.rndsystems.com
- 3. from Cleveland clinic website - http://www.clevelandclinicmeded.com/ Hepatocellular carcinoma
- 4. Comoglio et al., Nature Reviews 2008
- 5. Lipidoid-based nanoparticles with siRNA against Itgb1 Mouse with spontaneous MET/∆N-90-β-catenin-driven HCC Intravenous injection
- 6. Hepatocyte-specific Itgb1 knockdown in mouse liver Bogorad et al., Nature Communication 2014
- 7. The effect of integrin knockdown in liver in vivo Bogorad et al., Nature Communication 2014
- 8. The effect of integrin knockdown in liver in vitro Bogorad et al., Nature Communication 2014
- 9. The long-term downregulation of integrins in vivo Bogorad et al., Nature Communication 2014
- 10. The effects of Itgb1 downregulation on mouse
- 11. The effects of Itgb1 downregulation on spontaneous HCC Bogorad et al., Nature Communication 2014
- 12. The effects of Itgb1 downregulation on spontaneous HCC Bogorad et al., Nature Communication 2014
- 13. The effects of Itgb1 knockdown on expression
- 14. The effects of si-Itgb1 on MET protein maturation Bogorad et al., Nature Communication 2014
- 15. The Itgb1 knockdown affects pathway activation Bogorad et al., Nature Communication 2014
- 16. Lam et al., Molecular Therapy Nucleic Acids 2015
From R&D Systems website - www.rndsystems.com
Слайд 1Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice
Anton Krotov,
Слайд 5Lipidoid-based nanoparticles with siRNA against Itgb1
Mouse with spontaneous MET/∆N-90-β-catenin-driven HCC
Intravenous injection
Слайд 10The effects of Itgb1 downregulation on mouse and human HCC cells
Bogorad et al., Nature Communication 2014
Слайд 11The effects of Itgb1 downregulation on spontaneous HCC
Bogorad et al.,
Nature Communication 2014
Слайд 12The effects of Itgb1 downregulation on spontaneous HCC
Bogorad et al.,
Nature Communication 2014
Слайд 13The effects of Itgb1 knockdown on expression and signalling of MET
and β-catenin oncogenes
Bogorad et al., Nature Communication 2014
