There’s A 90% Chance Your Son Is Pregnant презентация

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Presenter and Contact Information Dale Sanders Senior Vice President, Strategy, Health Catalyst 801-708-6800 dale.sanders@healthcatalyst.com @drsanders www.linkedin.com/in/dalersanders/

Слайд 1Predicting The Future Of Predictive Analytics In Healthcare
There’s A 90% Chance

Your Son Is Pregnant

Слайд 2Presenter and Contact Information
Dale Sanders
Senior Vice President, Strategy, Health Catalyst
801-708-6800
dale.sanders@healthcatalyst.com
@drsanders
www.linkedin.com/in/dalersanders/



Слайд 3Acknowledgements
David Crockett, PhD, Health Catalyst
Eric Siegel, PhD, Columbia University
Ron Gault, Aerospace

Corporation, Northrup-Grumman, TRW
Wikipedia

Слайд 4The Goal Today
I hope you leave this webinar with…
Informed Expectations

and Opinions: Be generally aware of the realistic possibilities for predictive analytics in healthcare, over the next few years

The Right Questions: To be conversant in the concepts of predictive analytics and be able to ask reasonably well-informed questions of your analytics teams, especially vendors, during the strategic process of developing your organization’s predictive analytics strategy




Слайд 5
Agenda
Basic Concepts, Fundamental Assertions
Predictive Analytics Outside Healthcare
Predictive Analytics Inside Healthcare
Key Questions

To Ask Vendors And Your Analytics Teams




Слайд 6Sampling of My Background In Predictive Analytics


Слайд 7 Gartner 2014 Hype Cycle for Emerging Technology
Predictive Analytics in Healthcare, according

to Dale Sanders



Слайд 8“Beyond math, there are no facts; only interpretations.”

- Friedrich Nietzsche


Слайд 9Challenge of Predicting Anything Human


Слайд 10What Should We Expect In Healthcare?
Machines are predictable; humans aren’t
“People are

influenced by their environment in innumerable ways. Trying to understand what people will do next, assumes that all the influential variables can be known and measured accurately. People's environments change even more quickly than they themselves do. Everything from the weather to their relationship with their mother can change the way people think and act. All of those variables are unpredictable. How they will impact a person is even less predictable. If put in the exact same situation tomorrow, they may make a completely different decision. This means that a statistical prediction is only valid in sterile laboratory conditions, which suddenly isn't as useful as it seemed before.”

Gary King, Harvard University and the Director of the Institute for Quantitative Social Science


Слайд 11Healthcare Analytics Adoption Model
Level 8
Level 7
Level 6
Level 5
Level 4
Level 3
Level 2
Level

1

Level 0

Personalized Medicine & Prescriptive Analytics

Clinical Risk Intervention & Predictive Analytics

Population Health Management & Suggestive Analytics

Waste & Care Variability Reduction

Automated External Reporting

Automated Internal Reporting

Standardized Vocabulary & Patient Registries

Enterprise Data Warehouse

Fragmented Point Solutions

Tailoring patient care based on population outcomes and genomic data. Fee-for-quality rewards health maintenance.

Organizational processes for intervention are supported with predictive risk models. Fee-for-quality includes fixed per capita payment.

Tailoring patient care based on population metrics. Fee-for-quality includes bundled per case payment.

Reducing variability in care processes. Focusing on internal optimization and waste reduction.

Efficient, consistent production of reports & adaptability to changing requirements.

Efficient, consistent production of reports & widespread availability in the organization.

Relating and organizing the core data content.

Collecting and integrating the core data content.

Inefficient, inconsistent versions of the truth. Cumbersome internal and external reporting.

© Sanders, Protti, Burton, 2013


Слайд 12Concepts & Principles of Predictive Analytics


Слайд 13Semantics, Ssschmantics
Predictive Analytics and Predictive Models: These terms have their origins

in statisticians; e.g., understanding real-world phenomena such as healthcare, retail sales, customer relationship management, voting preferences, etc.

Machine Learning Algorithms: This term has its origins in computer scientists; e.g., natural language processing, speech recognition, image recognition, adaptive control systems in manufacturing, robots, satellites, automobiles and aircraft, etc.

As it turns out, the latter can be applied to the former, so the two schools of thought are now generally interchangeable. Don’t let vendors fool you into thinking that “machine learning” is more sophisticated or better than predictive modeling.


Слайд 14For Now, Just Know The Terms
And Know Where To Go For

Details

Слайд 15For Now, Just Know The Terms
And Know Where To Go For

Details

MachineLearningMastery.com


Слайд 16The Basic Process of Predictive Analytics


Слайд 17A Big & Common Mistake: Over Fitting
You train the model to

be very specific on a given data set, but the model cannot adapt to a new, unknown data set

Слайд 18Specificity vs. Sensitivity: Trading One For Another
Specificity:
The true negative rate.

For example, the percentage of diabetic patients identified who will not have a myocardial infarction

Sensitivity:
The true positive rate. For example, the percentage of diabetic patients that will have a myocardial infarction

Слайд 19Receiver Operating Characteristic (ROC) Plot
Tuning radar receivers in WWII
Maximum radar receiver

sensitivity led to many false positives… too many alarms
Lower radar receiver sensitivity led to many false negatives… missed threats
Same challenge in airport security screening systems and spam filters
Concept has been applied heavily in diagnostic medicine

True Positive Rate vs. False Positive Rate

Слайд 20Data Volume vs. Predictive Model
“But invariably, simple models and a lot

of data trump more elaborate models based on less data.”

“The Unreasonable Effectiveness of Data”, March 2009, IEEE Computer Society; Alon Halevy, Peter Norvig, and Fernando Pereira, Google


Слайд 21The Human Data Ecosystem


Слайд 22We Are Not “Big Data” in Healthcare Yet


Слайд 23Predictive Precision vs. Data Content


Слайд 24Thank you for the graphs, PreSonus
Healthcare and patients are continuous flow,

analog process and beings

But, if we sample that analog process enough, we can approximately recreate it with digital data

Remember Your Calculus Digital Sampling Theory?


Слайд 25We are asking physicians and nurses to act as our “digital

samplers”… and that’s not going to work

Слайд 26Predictive Analytics Outside Healthcare
Predictive Analytics Outside Healthcare


Слайд 27“Mr. Sanders, while your 9-year tenure as an inmate has been

stellar, our analytics models predict that you are 87% likely to become a repeat offender if you are granted parole. Therefore, your parole is denied.”

- 2014, 80% of parole boards now use predictive analytics for case management*

* The Economist, “Big data can help states decide whom to release from prison” April 19, 2014


Слайд 28
Thank you Sonja Star, New York Times
“Evidence Based” Sentencing

20 states use

predictive analytics risk assessments to inform criminal sentencing.

“Evidence Based” Sentencing


Слайд 29Recidivism Risk Assessment: Level of Service/Case Management Inventory (LS/CMI)*
15 different scales

feed the PA algorithm

Criminal history
Education/employment
Family/marital
Leisure/recreation
Companions
Alcohol/drug problems
Antisocial patterns
Pro-criminal attitude orientation

Barriers to release
Case management plan
Progress record
Discharge summary
Specific risk/needs factors
Prison experience - institutional factors
Special responsivity consideration

42.2% of high-risk offenders recidivate within 3 years

*Nov. 2012, Hennepin County, Minn. Department of Community Corrections and Rehabilitation


Слайд 30
“Since the publishing of Lewis' book, there has been an explosion

in the use of data analytics to identify patterns of human behavior and experience and bring new insights to fields of nearly every kind.”



Слайд 31
eHarmony Predictions
“Heart” ☺ of the system: Compatibility Match Processor (CMP)
320 profiling

questions/attributes per user
29 dimensions of compatibility
~75TB
20M users
3B potential matches daily
60M+ queries per day, 250 attributes

Thank you, Thod Nugyen, eHarmony CTO


Слайд 32Thank you, Ryan Barker, Principal Software Engineering – Matching, eHarmony
29 Dimensions

of Compatibility

Слайд 33Predictive Analytics Inside Healthcare


Слайд 34What Are We Trying to Predict?
Common applications being marketed today

Identifying preventable

re-admissions: COPD, MI/CHF, Pneumonia, et al
Sepsis
Risk of decubitus ulcers
LOS predictions in hospital and ICU
Cost-per-patient per inpatient stay
Cost-per-patient per year by disease and comorbidity
Risk of ICU mortality
Risk of ICU admission
Appropriateness of C-section
Emerging: Genomic phenotyping


Слайд 35True Population Predictive Risk Management
Thank you, for the diagram, Robert Wood

Johnson Foundation, 2014

Very Little ACO Influence

Very Little ACO Influence

>/=30% Waste*
100% ACO Influence

*Congressional Budget Office, IOM, “Best Care at Lower Cost”, 2013

True Population Health Management


Слайд 36Not all patients can functionally participate in a protocol

At Northwestern (2007-2009),

we found that 30% of patients fell into one or more of these categories:

Cognitive inability
Economic inability
Physical inability
Geographic inability
Religious beliefs
Contraindications to the protocol
Voluntarily non-compliant

Socioeconomic Data Matters


Слайд 37The key to predictive analytics in the future of health care

will be the ability to answer this two-part question:

What’s the probability of influencing this patient’s behavior towards our desired outcome and how much effort (cost) will be required for that influence?

Return on Engagement (ROE)


Слайд 38Return on Engagement (ROE)


Слайд 39Socioeconomic Data Matters


Слайд 40Development Partner


Слайд 41Flight Path “Outcomes”
Examples
Diabetes Cohort
Good Flight Path
Poor Flight Path
$ COST Per Member

Per Year (Charges)

For > 1 year of encounters

(~5 yrs and 26k patients)

These aren’t really outcomes… they are proxies for outcomes


Слайд 42True Outcomes
Good Flight Path
Poor Flight Path
Absence of:
Cardiovascular disease (angina, MI, stroke)
Nephropathy/End

stage renal
Diabetic retinopathy
Glaucoma
Cataracts
Lower extremity tissue narcosis, foot ulcers
Peripheral neuropathy
Diabetic ketoacidosis
Diabetic preeclampsia
GI complications (nausea, constipation)
Erectile dysfunction

Presence of:
Cardiovascular disease (angina, MI, stroke)
Nephropathy/End stage renal
Diabetic retinopathy
Glaucoma
Cataracts
Lower extremity tissue narcosis, foot ulcers
Peripheral neuropathy
Diabetic ketoacidosis
Diabetic preeclampsia
GI complications (nausea, constipation)
Erectile dysfunction

Diabetes Cohort

(~5 yrs and 26k patients)


Слайд 43Two Layers of Predictive Function
Risk scores
Simulation


Слайд 44Microsoft Azure: Cloud-Based Algorithms


Слайд 45Allina Health Readmissions Model*
Variables Considered
*- Thank you, Jonathan Haupt


Слайд 46Allina Compared To Other Models
Multiple logistic regression
5.2% of discharged patients in

high risk category

Слайд 47Allina’s Intervention To Reduce Risk
Transition of Care “Conferences”
Patients, families, care givers
15%

reduction in readmissions
100+ APR-DRGs affected
More patients utilizing post-acute care
Skilled Nursing Facility
Home Health
TCU

Слайд 48Predictive and prescriptive (suggestive) analytics in the same user interface
The efficacy

and costs of antibiotic protocols for inpatients

Thank you, Dave Claussen, Scott Evans, et al, Intermountain Healthcare

The Antibiotic Assistant


Слайд 49The Antibiotic Assistant Impact
Complications declined 50%

Avg. number of doses declined from

19 to 5.3

The replicable and bigger story
Antibiotic cost per treated patient: $123 to $52
By simply displaying the cost to physicians






Слайд 50Wrapping Up


Слайд 51Key Questions To Ask
Of Vendors and Your Analytics Teams
What is your

formal training, education, and practical experience in this field?
What are the input variables to the model?
What model and/or algorithms are you using and why?
How are you going to train the model?
Are you using our data or other organizations’ data for training? Why?
If you are using other organizations’ data, how are you going to customize the model to our specific data environment?




Слайд 52Action matters: What is the return in investment for intervention? Are

we prepared to invest more... or say “no”… to patients who score low on predicted engagement?
Human unpredictability: The mathematical models of human behavior are relatively immature.
Socio-economics: Can today’s healthcare ecosystem expand to make a difference?
Missing data: Without patient outcomes, the PA models are open loop.
Social controversy: How much do we want to know about the future of our health, especially when the predictive models are uncertain?
Wisdom of crowds: Suggestive analytics from “wise crowds” might be easier and more reliable than predictive analytics, until our data content improves



Closing Thoughts and Questions


Слайд 53Q & A
Submitted prior to the webinar
Submitted through the webinar chat

box

Слайд 54Thank You
For questions and follow-up, please contact me
dale.sanders@healthcatalyst.com
@drsanders

Upcoming Educational Opportunities

An Overview

of the Healthcare Analytics Market
Date: January 21, 2015, 1-2pm, EST
Host: Jim Adams, Executive Director, The Advisory Board

A Pioneer ACO Case Study: Quality Improvement in Healthcare
Date: January 28, 2015, 1-2pm, EST
Hosts:
Robert Sawicki, MD, Senior Vice President of Supportive Care, OSF HealthCare
Roopa Foulger, Executive Director Data Delivery, OSF HealthCare
Linda Fehr, RN, Division Director of Supportive Care, OSF HealthCare
 



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