Mycobacterium презентация

Содержание

Mycobacterium tuberculosis Mycobacterium leprae (uncommon) Mycobacterium avium-intracellulaire Complex (MAC) or (M. avium) Important Human Pathogens

Слайд 2

Слайд 3Mycobacterium tuberculosis
Mycobacterium leprae (uncommon)
Mycobacterium avium-intracellulaire Complex (MAC) or (M. avium)
Important Human

Pathogens

Слайд 4Lipid-Rich Cell Wall of Mycobacterium
CMN Group: Unusual cell wall lipids (mycolic

acids,etc.)

(Purified Protein Derivative)

Слайд 5Acid-Fast (Kinyoun) Stain of Mycobacterium
NOTE: cord growth (serpentine arrangement) of virulent

strains

Слайд 6Photochromogenic Mycobacterium kansasii on Middlebrook Agar
NOTE: Mycobacteria pathogenic for humans can

be differentiated (Runyon Groups) by:
speed of growth (all are slower than most other pathogens) and by
production of chromogenic pigments (in light, in dark, or none)

Слайд 7Improved Mycobacterial Isolation Medium

Слайд 8Eight Week Growth of Mycobacterium tuberculosis on Lowenstein-Jensen Agar

Слайд 9Pathogenic Mycobacterium spp.
BCG
AIDS patients

Слайд 10Mycobacterial Clinical Syndromes

Слайд 11Diagram of a Granuloma


NOTE: ultimately a fibrin layer develops

around granuloma (fibrosis), further “walling off” the lesion.
Typical progression in pulmonary TB involves caseation, calcification and cavity formation.

Слайд 12Laboratory Diagnosis of Mycobacterial Disease

Слайд 13Differential Characteristics of Commonly Isolated Mycobacterium spp.

Слайд 15Mycobacterium tuberculosis

Слайд 16Mycobacterium tuberculosis Infections

Слайд 17Incidence of Tuberculosis in USA

Слайд 18Mycobacterium tuberculosis Infections (cont.)
BCG (bacille Calmette-Guerin) = attenuated M. bovis
Positive PPD

+ Chest X-Ray +

MDR-TB a serious global health threat

Слайд 19Pneumonia
Granuloma formation with fibrosis
Caseous necrosis
Tissue becomes dry & amorphous (resembling cheese)
Mixture

of protein & fat (assimilated very slowly)
Calcification
Ca++ salts deposited
Cavity formation
Center liquefies & empties into bronchi

Typical Progression of Pulmonary Tuberculosis

Слайд 20PPD Tuberculosis Skin Test Criteria
PPD = Purified Protein Derivative from M.

tuberculosis

Слайд 21Chest X-Ray of Patient with Active Pulmonary Tuberculosis

Слайд 22Mycobacterium Tuberculosis Stained with Fluorescent Dye

Слайд 24Mycobacterium leprae

Слайд 25Mycobacterium leprae Infections

Слайд 26Mycobacterium leprae Infections (cont.)

Слайд 27Tuberculoid vs. Lepromatous Leprosy
Clinical Manifestations and Immunogenicity

Слайд 28Lepromatous vs. Tuberculoid Leprosy

Слайд 29Lepromatous Leprosy (Early/Late Stages)

Слайд 30Lepromatous Leprosy Pre- and Post-Treatment

Слайд 31Clinical Progression of Leprosy

Слайд 32Effect of Cell-Mediated Immunity on Leprosy Clinical Outcome

Слайд 34Mycobacterium avium-intracellulaire Complex (MAC)

Слайд 35Mycobacterium avium-intracellulaire Infections

Слайд 36Mycobacterium avium-intracellulaire Infections

Слайд 37M. avium-intracellulaire Complex (MAC) Progression vs. CD4 Count in AIDS Patients

Слайд 38Mycobacterium avium-intracellulaire in Tissue Specimens
Low Magnification
High Magnification

Слайд 40REVIEW
of
Mycobacterium

Слайд 41Mycobacterium tuberculosis
Mycobacterium leprae (uncommon)
Mycobacterium avium-intracellulaire Complex (MAC) or (M. avium)
Important Human

Pathogens

REVIEW

Слайд 42Lipid-Rich Cell Wall of Mycobacterium
CMN Group: Unusual cell wall lipids (mycolic

acids,etc.)

(Purified Protein Derivative)

REVIEW

Слайд 43Pathogenic Mycobacterium spp.
BCG
AIDS patients
REVIEW

Слайд 44Mycobacterial Clinical Syndromes
REVIEW

Слайд 45Diagram of a Granuloma


NOTE: ultimately a fibrin layer develops

around granuloma (fibrosis), further “walling off” the lesion.
Typical progression in pulmonary TB involves caseation, calcification and cavity formation.

REVIEW

Слайд 46Review of Mycobacterium tuberculosis

Слайд 47Mycobacterium tuberculosis Infections
REVIEW

Слайд 48Mycobacterium tuberculosis Infections (cont.)
BCG (bacille Calmette-Guerin) = attenuated M. bovis
Positive PPD

+ Chest X-Ray +

MDR-TB a serious global health threat

REVIEW

Слайд 49Pneumonia
Granuloma formation with fibrosis
Caseous necrosis
Tissue becomes dry & amorphous (resembling cheese)
Mixture

of protein & fat (assimilated very slowly)
Calcification
Ca++ salts deposited
Cavity formation
Center liquefies & empties into bronchi

Typical Progression of Pulmonary Tuberculosis

REVIEW

Слайд 50Review of Mycobacterium leprae

Слайд 51Mycobacterium leprae Infections
REVIEW

Слайд 52Mycobacterium leprae Infections (cont.)
REVIEW

Слайд 53Lepromatous vs. Tuberculoid Leprosy
REVIEW

Слайд 54Lepromatous Leprosy (Early/Late Stages)
REVIEW

Слайд 55Clinical Progression of Leprosy
REVIEW

Слайд 56Effect of Cell-Mediated Immunity on Leprosy Clinical Outcome
REVIEW

Слайд 57Review of Mycobacterium avium-intracellulaire Complex (M. avium)

Слайд 58Mycobacterium avium-intracellulaire Infections
REVIEW

Слайд 59Mycobacterium avium-intracellulaire Infections
REVIEW

Слайд 60M. avium-intracellulaire Complex (MAC) Progression vs. CD4 Count in AIDS Patients
REVIEW

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