Biochemical reaction kinetics презентация

Chemical kinetics studies the rate and mechanism of chemical reactions

Слайд 1 Zaporizhzhya State Medical University Analytical Chemistry Department BIOCHEMICAL REACTION KINETICS Lecturer: Monaykina Yulia Vitalievna 2016


Слайд 2Chemical kinetics studies the rate and mechanism of chemical reactions


Слайд 3 In homogeneous reactions all the reactants exist in the same phase

in which the reaction itself occurs. Na2CO3 + HCl ↔ NaHCO3 + NaCl Heterogeneous reactions take place only in the interphase. Fe + HCl→FeCl2 +H2




Слайд 4

Single-stage reactions are called simple
(or elementary) reactions.


Multistage reactions include

few simple reactions and are called complex
(or non-elementary) reactions.




All biochemical reactions are non-elementary.

Слайд 5 The dependence of the reaction rate on the concentration of reactants

is described by the law of mass action discovered by N.Beketov, C. Guldberg and P. Waage in 1967:

«At constant temperature the rate of chemical reaction is in direct proportion to the product of reactant concentrations in the degree of their stoichiometric coefficients».

Слайд 6Mathematical expression of the law of mass action is called a
kinetic

equation
or
rate law of the reaction.

Слайд 7Molecularity of the reaction
is determined by the number of molecules

which interact and take part in an elementary act of the reaction.

Слайд 8 Arrenius Equation establishes a connection between the reaction rate constant, activation

energy and temperature:







e is base of natural logarithm;
R is universal gas constant (8.314 J / mol · K);
T is absolute temperature, K;
A is pre-exponential factor.



Слайд 9Catalysis is the change of chemical reactions rate under the influence

of substances, the amount and nature of which, after completion of the reaction are the same as before the reaction.

Catalyst is a substance that influences the rate of chemical processes without changing its own chemical composition.


Слайд 10

Enzymes are catalysts of the chemical reactions in the body.

An

enzyme is a protein that catalyses a chemical reaction by lowering the activation energy.


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